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Vittorio Saba Selected Research

temporin

4/2008Temporin A is effective in MRSA-infected wounds through bactericidal activity and acceleration of wound repair in a murine model.
7/2006Interaction of antimicrobial peptide temporin L with lipopolysaccharide in vitro and in experimental rat models of septic shock caused by gram-negative bacteria.
11/2005Temporin A alone and in combination with imipenem reduces lethality in a mouse model of staphylococcal sepsis.
8/2004Temporin A soaking in combination with intraperitoneal linezolid prevents vascular graft infection in a subcutaneous rat pouch model of infection with Staphylococcus epidermidis with intermediate resistance to glycopeptides.
8/2003Prophylactic efficacy of topical temporin A and RNAIII-inhibiting peptide in a subcutaneous rat Pouch model of graft infection attributable to staphylococci with intermediate resistance to glycopeptides.
11/2002Temporin A as a prophylactic agent against methicillin sodium-susceptible and methicillin sodium-resistant Staphylococcus epidermidis vascular graft infection.

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Vittorio Saba Research Topics

Disease

26Infections
04/2009 - 09/2002
20Sepsis (Septicemia)
04/2009 - 07/2002
14Septic Shock (Toxic Shock Syndrome)
10/2008 - 01/2002
11Staphylococcal Infections
09/2008 - 10/2003
7Bacteremia
11/2007 - 02/2005
5Body Weight (Weight, Body)
09/2008 - 01/2002
5Inflammation (Inflammations)
08/2007 - 04/2004
4Atherosclerosis
08/2007 - 04/2004
3Pseudomonas Infections
12/2008 - 12/2007
3Wounds and Injuries (Trauma)
06/2008 - 01/2008
3Carotid Stenosis (Carotid Artery Stenosis)
04/2008 - 04/2004
3Peritonitis
01/2008 - 11/2002
3Catheter-Related Infections
09/2006 - 10/2005
2Obstructive Jaundice (Cholestatic Jaundice)
11/2006 - 09/2006
2Dyslipidemias (Dyslipidemia)
12/2005 - 08/2005
2Shock
02/2005 - 02/2004
2Necrosis
09/2004 - 01/2002
1Gram-Negative Bacterial Infections
12/2008
1Neutropenia
10/2008
1Infertility (Sterility)
07/2008
1Surgical Wound
04/2008
1Carotid Artery Diseases
04/2008
1Wound Infection (Wound Infections)
01/2008
1Intraabdominal Infections
01/2008
1Neoplasms (Cancer)
10/2007
1Adenocarcinoma
10/2007
1Transient Ischemic Attack
07/2007
1Stroke (Strokes)
07/2007
1Endotoxemia
09/2006

Drug/Important Bio-Agent (IBA)

18Anti-Bacterial Agents (Antibiotics)IBA
09/2008 - 02/2003
10Peptides (Polypeptides)IBA
09/2008 - 01/2002
10EndotoxinsIBA
11/2006 - 01/2002
8RNAIII inhibiting peptideIBA
06/2008 - 08/2003
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2007 - 01/2002
7Antimicrobial PeptidesIBA
12/2008 - 12/2004
6VancomycinFDA LinkGeneric
07/2008 - 10/2003
6temporinIBA
04/2008 - 11/2002
6LipopolysaccharidesIBA
01/2008 - 06/2003
6GlycopeptidesIBA
04/2007 - 09/2002
6CathelicidinsIBA
09/2006 - 01/2004
5Polyethylene Terephthalates (Polyethylene Terephthalate)IBA
06/2007 - 09/2002
5ImipenemFDA Link
07/2006 - 07/2002
4Rifampin (Rifampicin)FDA LinkGeneric
04/2009 - 06/2006
4SolutionsIBA
07/2008 - 01/2002
4BMAP-28IBA
07/2008 - 12/2004
4ZincIBA
04/2008 - 04/2004
4Linezolid (Zyvox)FDA Link
11/2007 - 10/2003
4Interleukin-6 (Interleukin 6)IBA
08/2007 - 04/2004
4PiperacillinFDA LinkGeneric
07/2006 - 01/2002
3Tachypleus tridentatus tachyplesin peptideIBA
12/2008 - 12/2007
3TeicoplaninIBA
06/2008 - 12/2007
3Pharmaceutical PreparationsIBA
05/2008 - 07/2004
3Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric
01/2008 - 12/2007
3MetallothioneinIBA
08/2007 - 12/2005
3MagaininsIBA
02/2005 - 01/2002
3Sodium ChlorideFDA LinkGeneric
07/2004 - 01/2002
2buforin IIIBA
04/2009 - 07/2002
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2008 - 01/2008
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
09/2008 - 01/2008
2distinctinIBA
09/2008 - 04/2007
2indolicidinIBA
01/2008 - 07/2002
2antimicrobial peptide IB-367 (iseganan)IBA
11/2007 - 11/2003
2CytokinesIBA
08/2007 - 08/2005
2Interleukin-10 (Interleukin 10)IBA
08/2007 - 04/2004
2AgarIBA
06/2007 - 08/2003
2ExotoxinsIBA
09/2006 - 02/2005
2Proteins (Proteins, Gene)FDA Link
05/2006 - 08/2003
2quinupristin-dalfopristin (Synercid)FDA Link
10/2005 - 09/2002
2pexigananIBA
02/2005 - 09/2004
2Polymyxin B (Aerosporin)FDA LinkGeneric
07/2004 - 01/2002
2Levofloxacin (Levaquin)FDA Link
10/2003 - 01/2002
1Clarithromycin (Biaxin)FDA LinkGeneric
12/2008
1Colony-Stimulating Factors (Colony Stimulating Factor)IBA
10/2008
1antineoplaston A10 (A 10)IBA
07/2008
1allevynIBA
06/2008
1hamamelitanninIBA
05/2008
1Codon (Codons)IBA
04/2008
1LipidsIBA
08/2007
1Lipopolysaccharide ReceptorsIBA
08/2007
1Polymethyl Methacrylate (Sol)IBA
07/2007
1Colistin (Coly-Mycin)FDA Link
07/2007
1MetalsIBA
07/2007
1ChemokinesIBA
07/2007
1LipopeptidesIBA
06/2007
1Pal-Lys-Lys-NH2IBA
06/2007
1lysyllysine (Lys-Lys)IBA
06/2007
1BMAP-27IBA
11/2006
1tritrpticinIBA
08/2006

Therapy/Procedure

11Ligation
01/2008 - 07/2002
11Punctures
01/2008 - 07/2002
10Intraperitoneal Injections
10/2008 - 01/2002
6Central Venous Catheters
11/2007 - 10/2005
3Stents
07/2008 - 12/2007
3Prostheses and Implants (Prosthesis)
06/2007 - 08/2003
2Therapeutics
10/2008 - 06/2008
2Antibiotic Prophylaxis
07/2008 - 06/2006
2Drug Therapy (Chemotherapy)
01/2008 - 10/2007
1Operative Surgical Procedures
07/2008
1Radiotherapy
10/2007
1Chemoradiotherapy
10/2007